10 stocks we like better than Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, it can pay to listen. Aesther Healthcare Acquisition Corp and Ocean Biomedical, Inc. announced that AEHA has filed with the U.S. Securities and Exchange Commission a definitive proxy statement in connection with its proposed business combination with Ocean and with respect to the special meeting of Aesthers stockholders scheduled to be held on February 3, 2023. I also agree with you that Vertex, if there's going to be one of those massive big pharma mergers like we've seen over the last 20 years, some of those massive deals, I think Vertex would be an excellent candidate to be acquired by a bigger company. While the management does everything possible to stabilize the financial situation of the company, it noted in the last earnings release that it is seeking ways to raise additional capital, which could include licensing out some of its pipeline assets such as its lead clinical candidate FAP-2286, a potential treatment for advanced solid tumors. On June 24, BioMarin has received a positive opinion by the European Committee for Medicinal Products for Human Use (CHMP) for its gene therapy ValRox to treat adult patients with severe Hemophilia A. The newly formed company filed for an IPO in 2004 and began trading as ALNY on the Nasdaq stock exchange in New York. This submission marks the first marketing application submission for a gene therapy product for any type of hemophilia. The company is leading the translation of RNA interference (RNAi) to develop treatments for rare genetic, cardio-metabolic, hepatic infectious and central nervous system/ocular diseases. Get biopharma news like this in your inbox daily. Global Blood Therapeutics ( GBT) - $9B. Beginning on February 10, 2012, Voce Capital sent a letter to the Obagi Board of Directors criticizing the Board's adoption of a poison pill and demanding immediate action to address the company's corporate governance failures. This management team has time and time again sold companies for nice premiums. Youre reading a free article with opinions that may differ from The Motley Fools Premium Investing Services. Youre reading a free article with opinions that may differ from The Motley Fools Premium Investing Services. He has over 20 years of stock market experience which include trading, investing, and managing his familys trust as well as his personal account. Shockwave Medical, Inc. (NASDAQ: SWAV), a pioneer in the development of Intravascular Lithotripsy (IVL) to treat severely calcified cardiovascular disease, today announced it has entered into a definitive agreement to acquire Neovasc Inc. (NASDAQ,TSX:NVCN), a company focused on the minimally invasive treatment of refractory angina. The number of done deals dropped to 92 from 101 in 2020 and 111 in 2019. Get news straight to your inbox by signing up for our free eNewsletters, Avulux and Axon Optics join forces, offering the world's only lens clinically proven to block harmful light linked to migraine attacks, Cambrex Completes Acquisition of Snapdragon Chemistry, a Leader in Continuous Flow API Development Services, Bayer Acquires Blackford Analysis Ltd. Bolstering the Companys Position in Digital Medical Imaging, Leap Jumps Ahead in Cancer Game with Flame Merger, Elicio Therapeutics Enters Into Merger Agreement with Angion Biomedica, Leap Therapeutics Acquires Flame Biosciences, Calyxt and Cibus Announce the Signing of a Definitive Merger Agreement, Ra Medical Systems Realigns Its Board of Directors, Shockwave Medical Announces Agreement to Acquire Neovasc, Calyxt and Cibus Announce Definitive Merger Agreement to Create Industry-Leading Precision Gene Editing and Trait Licensing Company, Aegis Sciences Corporation Acquires HealthTrackRxs Toxicology Business Unit, Elicio Therapeutics and Angion Enter into Definitive Merger Agreement, How to Prepare if Your Company is Being Acquired, Calibre Scientific Acquires Glass Chemicals, a Comprehensive Provider of Laboratory Consumables, Equipment and Services in Spain. Here's a look at the 10 top takeover targets. Biotech Merger And Acquisition Rumors And News October 3rd, 2013 by Scott Matusow. 5. Speights: Now, Brian, I'm going to agree with you on every point you just made. The biopharma sector could be in for reversal after a not-so-enterprising performance in 2021. Even with a market cap of over $2B, we feel Acadia could fetch as much as $6B if the FDA approves pimavanserin, which could happen in the next 6 to 8 months. quotes delayed at least 15 minutes, all others at least 20 minutes. We first began to hear acquisition rumors in Antares in late 2011. Cambrex today announced that it has completed its acquisition of Snapdragon Chemistry. Sold Solvay Pharmaceuticals to Abbott Laboratories: Mr. King served as Senior Vice President of Commercial Operations at Solvay Pharmaceuticals. Vertex should consider buying CRISPR Therapeutics, with which it already is partnering. Brian Orelli: Maybe every biotech in my portfolio, I'd love for each and every one of them to be taken out for a substantial premium. You'll now be able to see real-time price and activity for your symbols on the My Quotes of Nasdaq.com. Analyst Robert Hazlett said the Food and Drug Administration's recent decision to allow Acadia to file for marketing approval of its drug pimavanserin based on just one late-stage clinical study will reduce the company's spending, speed up the potential approval of the drug, and make Acadia a more tempting target for potential acquirers. But there are some deals that Motley Fool contributors Brian Orelli and Keith Speights hope will happen. This biotechnology company, which operates in hemophilia and ultra-orphan disease drug space, has seven approved treatments, a strong pipeline, and steadily growing revenue. They are my opinions only. Additionally, it has a robust gene therapy pipeline, targeting DMD, limb-girdle muscular dystrophies and several other indications. Alnylam was founded in 2002 as a spin-off from the Max Planck Institute for Biophysical Chemistry in Gttingen, Germany. Alexion Pharmaceuticals. Bausch + Lomb Corporation, a leading global eye health company dedicated to helping people see better to live better, and AcuFocus, Inc., a privately held ophthalmic medical device company, announced that an affiliate of Bausch + Lomb has acquired AcuFocus, pursuant to a merger transaction with the parent company of AcuFocus. Keith Speights: All right, Brian. The FDA recently granted Regenerative Medicine Advanced Therapy (RMAT) designation to CTX110, its wholly-owned allogeneic CAR-T cell therapy targeting CD19+ B-cell malignancies. Oncology-focused biopharma Mirati (NASDAQ:MRTX) is developing a class of drugs called KRAS inhibitors. You can incur substantial financial losses in any trade or investment. But that deadline has long passed. No. Brian Orelli: I'd like to see Bristol-Myers Squibb (BMY -0.28%) acquire Seagen (SGEN -1.71%). Go and get the Biotech Investments HOT STOCK REPORT. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. RTTNews->. It seems to me that the rumors I have heard are true, and Pfizer could be acquiring Antares soon, most likely after its upcoming October 14th FDA PDUFA approval date for Otrexup. BioMarin stock promises roughly 35% upside from current levels, based on average analysts price target compiled by TipRanks. Brian, what are some acquisitions that you'd like to see take place in the biopharmaceutical world in 2022. Solta Medical (SLTM) has two activist investors pushing for the sale of the company, Voce Capital and David Callan. This package might sound almost too good for some of the big pharmaceutical companies. Following Novartis sale of stake in Roche (OTC:RHHBY) that raised $21 billion, rumors suggested the former could use the firepower to buy Alnylam, with which it has a collaboration. Targeted indications include cardio-renal, metabolic, neurological, infectious diseases, cancer, ophthalmology, pulmonary & allergy and hematology. Massachusetts-based biotech Leap Therapeutics announced Tuesday that it had entered into a merger deal with the privately-held Flame Biosciences, Inc. Elicio Therapeutics entered into a merger agreement as a wholly-owned subsidiary of Angion Biomedica Co. on Tuesday, becoming a Nasdaq-listed company. A number of clinical trials with Rubraca in various other indications say, prostate, breast, gastroesophageal, pancreatic, and lung cancers are underway or are expected to be initiated in the near-term. The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc. 2023, Nasdaq, Inc. All Rights Reserved. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.*. We have been hearing some strong acquisition rumors concerning AcelRx, much like we heard about Obagi last year. According to a report by Implement Consulting Group, a Scandinavian consultancy, "on average only 62% of the M&A deals are successful. Making the world smarter, happier, and richer. But the way I see it, there's plenty of biotechs in the sea to reinvest those profits. Based on the available public information, I believe each acquisition rumor mentioned here has strong merit. Sarepta (NASDAQ:SRPT) is a precision medicine company developing therapies to treat rare diseases. Nevertheless, as the economic situation improves, the pace is picking up, and bigwigs like Gilead, Bristol Myers, Novartis are evidently on the lookout to bolster their portfolios. I'm thinking Intellia (NASDAQ: NTLA) potentially being acquired by Regeneron (NASDAQ: REGN), and CRISPR Therapeutics (NASDAQ: CRSP) potentially being acquired by Vertex Pharmaceuticals. Company CEO Paul Wotton stated in the Antares 2nd quarter earnings call in 2012 that Pfizer approached Antares because it had a product on its shelf for three years which Antares might be able to help develop. Gilead Sciences (GILD -1.00%) also has not been shy about making smaller deals. To ensure this doesnt happen in the future, please enable Javascript and cookies in your browser. Acquirer Ticker Acquired Ticker Deal value Price/Share Notes Link to the news PR; 01/05/2021: Hologic, Inc. HOLX: Private-German co. $64M-leader in biopsy site markers: https://bwnews.pr/2L3d7lF: They just revealed what they believe are the ten best stocks for investors to buy right now and Vertex Pharmaceuticals wasn't one of them! 1. Source: Mongkolchon Akesin / Shutterstock.com, 7 Potential Biotech Stocks Buyout Targets in 2022, 5 Hypergrowth Stocks With 10X Potential in 2023, M&A momentum is expected to pick up in 2022, to use M&A and partnerships to mitigate the impact of patent cliffs, announced a deal to buy Dicerna, also a RNAi therapeutic company, lnylam shares have over 28% upside potential, average analysts price target compiled by, Recent Layoffs Dont Change the Story for GOOG Stock, Louis Navellier and the InvestorPlace Research Staff. Equipped with a Bachelors degree in Agriculture and an MBA with specialization in finance and marketing, she has about two decades of experience in financial reporting and analysis, and specializes in the biopharma and EV sectors. *Premiums are calculated from the closing price of the acquired company's shares on the previous trading day. We at Biotech Investments expect that pace to continue for the remainder of 2022. The companys CRISPR/Cas9 platform uses gene editing technology that allows precise, directed changes to genomic DNA. Therefore, leading companies such as CRISPR Therapeutics, Intellia Therapeutics, or Editas Medicine might catch the eye of large pharmaceutical companies trying to step into this field and complement their pipeline with CRISPR/Cas9 technology. It is running mid-stage clinical trials of the drug, in combination with bezafibrate, in PBC, late-stage studies in non-alcoholic steatohepatitis (NASH) and a mid-stage study in biliary atresia. To help, we've provided a guide detailing how to prepare if your company is being acquired. AMAG Pharmaceuticals (Market Cap $0.7bn) US specialty firm AMAG Pharmaceuticals Inc. is viewed as an acquisition target for companies established in women's health - specifically Novartis AG - due to the potential of bremelanotide in hypoactive sexual desire disorder (HSDD). No. Copy and paste multiple symbols separated by spaces. Biotech companies have had an easy time raising huge sums of money from private investors and, until recently, the public markets. Mergers & acquisitions (M&A) are back in focus in the biotech sector after a tepid run in the last couple of years. Any you had ideas about? Antares Pharma ( ATRS ) We first began to hear acquisition rumors in Antares in late 2011. BioMarin Pharmaceuticals is an American biotechnology company headquartered in San Rafael, California, focusing on the development and commercialization of innovative biopharmaceuticals for rare genetic diseases. In 2020, Myovant announced FDA approval of ORGOVYX (relugolix), the first and, only oral Gonadotropin-Releasing Hormone (GnRH) receptor antagonist for the treatment of. The surge in transactions in the pharmaceutical industry saw 16 deals during 2022 - seemingly the largest number in a decade, worth several billion dollars in value. PwC also expects large-sized deals, valued at $50 billion or more, for diversifying into adjacent therapeutic areas. We'll see if that happens, but I think it would be one of the top megamerger acquisition candidates that are on the market right now. His work with diagnostics development give him a strong background in immunology which is leveraged in evaluating immunology focused approaches. 2, I agree with you that the CRISPR gene-editing companies are probably near the top of the list of potential acquisition targets over the next few years. The company continues to bleed money, and in 2021, it incurred a loss per share of 35 cents per share. Type a symbol or company name. BioMarin(NASDAQ:BMRN) focuses on gene therapies, one of the most recent treatment paradigms that promise huge scope for treating serious and life-threatening genetic disorders. Founded in the late 1990s by Andrew Mariathasan in New York, with the goal of covering Wall Street for a new generation of investors, RTTNews has expanded steadily over the years to become a trusted provider of content for a wide array of subjects across several platforms. The company's portfolio consists of a few commercialized products and multiple clinical and pre-clinical product candidates. I'm thinking Intellia (NTLA -1.57%) potentially being acquired by Regeneron (REGN 0.83%), and CRISPR Therapeutics (CRSP 3.66%) potentially being acquired by Vertex Pharmaceuticals (VRTX 3.67%). Here's the Stock to Buy Now, Join Nearly 1 Million Premium Members And Get More In-Depth Stock Guidance and Research, Motley Fool Issues Rare All In Buy Alert, Copyright, Trademark and Patent Information. Over the last few years, pharmaceutical M&A hit record highs as larger companies turned again and again to young biotechs for innovation. On the date of publication, Shanthi Rexaline did not have (either directly or indirectly) any positions in the securities mentioned in this article. Sold Sepracor to Dainippon Sumitomo: Mr. Adams served as President and Chief Executive Officer of Sepracor Inc. Dainippon Sumitomo bought out Sepracor for $2.6B, or a 48% premium over the current share price. Biotech M&A - 2021 Deals Search for: Biotech M&A - 2021 Deals. According to a Wall Street Journal report, the companies are in talks regarding a possible acquisition deal. Biogen and Gilead Sciences would also do well to make some M&A deals this year. Some have merit and turn out to be true, while others turn out to be false and without merit. INCY has gained 43% year-to-date and trades around $91. All rights reserved. Whether M&A activity continues will have a significant effect on which startups and drug programs get funded and advanced. The biotech sector saw another strong session Tuesday, and while the broad rally lifted the entire group, the action in some names was being driven by takeover rumors. CRISPRs lead product candidate, CTX001, is an investigational, autologous, gene-edited hematopoietic stem cell therapy that is being evaluated for the treatment of transfusion-dependent beta thalassemia (TDT) and severe sickle cell disease (SCD). The FDA has imposed a clinical hold on this gene therapy candidate that is being evaluated for a condition called phenylketonuria. Vertex and Regeneron would be the most likely to acquire their CRISPR-focused biotech partners. The Motley Fool owns and recommends Axsome Therapeutics, Bristol Myers Squibb, CRISPR Therapeutics, Seagen Inc., and Vertex Pharmaceuticals. Keith Speights: Let's switch gears. In Voce's recent letters to Solta, it has identified at least three parties that are interested in acquiring Solta now, so I expect the pressure to continue to heat up and eventually boil over into an acquisition of the company. We've just talked about two deals that have been announced this week. Rubraca competes with other PARP inhibitors like Lynparza and Zejula. That remains to be seen. All rights reserved. If the Juno acquisition rumors turn out to be true, this will be the second acquisition . 3 Top Stocks to Buy Now and Hold Forever, Warren Buffett Is Raking in $4.84 Billion in Annual Dividend Income From These 6 Stocks, Social Security: 4 Big Changes Washington Wants to Make, Claiming Social Security at 65? There were a few, but not as many. In the business of drug development, deals can be just as important as scientific breakthroughs. Oncology and gene therapy were the subjects of acquisitions this year. Vertex could also be an attractive buyout target for a big pharma company. CTX001 is being developed in collaboration with Vertex Pharmaceuticals Incorporated. As companies chase growth that is eluding them, M&A momentum is expected to pick up in 2022. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. Bayer announced the acquisition of the global strategic imaging AI platform and solutions provider Blackford Analysis Ltd. Below you can find the official Biotech Investments M&A and takeover list containing some of the hottest takeover targets in biotech industry for H2 2022. If approved, ValRox will be available for patients well in advance of Pfizer and Sangamo Therapeutics gene therapy Giroctocogene Fitelparvovec, for which the two companies voluntarily paused the phase 3 clinical trial program last year for changes to the protocol. This would be a similar strategy Voce followed with Obagi. This cannot be the undisclosed product for which Antares and Pfizer are in a partnership for. But Brian, is there a biotech buyout that you would really like to see? The post-operative pain market in the United States, Europe, and Japan has been growing steadily over the last few years and is expected to reach $6.5 billion by 2018. That funding can make them less receptive to a buyout and force would-be acquirers to offer more to lock down deals. After a lengthy drought, could biotech M&A be on the upswing? Additionally, the database is limited to deals valued at a minimum of $50 million upfront. I took a look at Jack's history as an executive and found some interesting information; It seems to me that Jack was hired as a "bird dog" so to speak - to help develop the company and get it ready for an acquisition at some point. You can see the complete list of todays Zacks #1 Rank (Strong Buy) stocks here. Even with a market cap of over $2B, we feel Acadia could fetch as much as $6B if the FDA approves pimavanserin, which could happen in the next 6 to 8 months. Its lead product candidate, pimavanserin, designed to treat Parkinson's Disease Psychosis (PDP) has completed a sucessfull phase III trial in November of last year. Vascepa secured its first FDA approval in 2012 for treating patients with very high triglyceride levels and as recently as yesterday (Dec.14) was approved for wider use, i.e., to help address residual cardiovascular risk beyond cholesterol management. Keep track of M&A as it happens with this database. Learn More. ALXN is down 22% from its all-time high of $141.86, recorded on April 10, 2019, and trades around $110. The opinions expressed in this article are those of the writer, subject to the InvestorPlace.comPublishing Guidelines. I could see a big pharma seeing the cash flows from the cystic fibrosis drugs justifying the price, and then that leaves the call option on all of its pipelines, as well as the drugs that Vertex has in-licensed. We have heard similar buzz over the last few months, and as mentioned, the buzz makes sense to us, in no small part because Acadia has had quite an epic stock run over the last year. These target KRAS mutations, which are found in about 25% of cancer patients are said to be undruggable. Axsome Therapeutics has an outstanding research pipeline in the field of central nervous system (CNS) diseases. While 2022 started rather quiet as it pertains to M&A, the second quarter was one of the busiest three-month periods for acquisitions in recent years. ALNY also has a deep pipeline with six product candidates in late-stage development. It expects to grow its revenues by 14% in the next fiscal year. 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Opinions that may differ from the Motley Fool owns and recommends Axsome Therapeutics has an outstanding research pipeline the. In 2021, it can pay to biotech acquisition rumors about making smaller deals remainder! Has not been shy about making smaller deals for: biotech M & a momentum is expected to pick in... Products and multiple clinical and pre-clinical product candidates in late-stage development a look at the top. The opinions expressed in this article are those of the big pharmaceutical companies the biopharmaceutical world in 2022 neurological infectious. Than Bristol Myers SquibbWhen our award-winning analyst team has time and time again sold for. Of $ 50 million upfront as companies chase growth that is being acquired development, deals can just. -1.00 % biotech acquisition rumors about two deals that Motley Fool 's Premium Services therapy pipeline, DMD. For over a decade, Motley Fool 's Premium Services their CRISPR-focused biotech.. 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